Yıl 2017, Cilt 47, Sayı 2, Sayfalar 72 - 76 2017-10-18

Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents

Sibel Döşler [1]

141 280

Recently, because of the rising in multidrug resistance from infectious agents, there is a prompted interest for the development of new antimicrobial agents and new therapeutic strategies to combat the infections caused by the resistant bacteria. Among them, the natural bactericidal compounds, such as antimicrobial cationic peptides (AMPs) seems very promising agents. AMPs are the important component of the innate immune response to the surrounding microorganisms. This substances which can be isolated from most of the living organisms, have various activity like broad spectrum antibacterial, antifungal, antiviral, and antiprotozoal. However there are some resistance mechanisms that affects the AMPs, because of the rapid action and existing more than one mechanism of action, development of resistance to AMPs is quite rare. Due to their many advantages and characteristics, AMPs looks like a good candidate for being a new generation, active antimicrobial agent for antimicrobial chemotherapy against especially multi drug resistant bacteria and biofilms, either alone or in combination. 
Antimicrobial peptides, antibiotic, resistance
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Konular Farmakoloji ve Eczacılık
Dergi Bölümü Review
Yazarlar

Yazar: Sibel Döşler
Kurum: Department of Pharmaceutical Microbiology, Faculty of Pharmacy, İstanbul University, 34116, İstanbul-Turkey
Ülke: Turkey


Bibtex @derleme { iujp345001, journal = {Istanbul Journal of Pharmacy}, issn = {2548-0731}, eissn = {2587-2087}, address = {İstanbul Üniversitesi}, year = {2017}, volume = {47}, pages = {72 - 76}, doi = {}, title = {Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents}, key = {cite}, author = {Döşler, Sibel} }
APA Döşler, S . (2017). Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents. Istanbul Journal of Pharmacy, 47 (2), 72-76. Retrieved from http://www.dergipark.gov.tr/iujp/issue/31503/345001
MLA Döşler, S . "Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents". Istanbul Journal of Pharmacy 47 (2017): 72-76 <http://www.dergipark.gov.tr/iujp/issue/31503/345001>
Chicago Döşler, S . "Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents". Istanbul Journal of Pharmacy 47 (2017): 72-76
RIS TY - JOUR T1 - Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents AU - Sibel Döşler Y1 - 2017 PY - 2017 N1 - DO - T2 - Istanbul Journal of Pharmacy JF - Journal JO - JOR SP - 72 EP - 76 VL - 47 IS - 2 SN - 2548-0731-2587-2087 M3 - UR - Y2 - 2017 ER -
EndNote %0 Istanbul Journal of Pharmacy Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents %A Sibel Döşler %T Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents %D 2017 %J Istanbul Journal of Pharmacy %P 2548-0731-2587-2087 %V 47 %N 2 %R %U
ISNAD Döşler, Sibel . "Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents". Istanbul Journal of Pharmacy 47 / 2 (Ekim 2017): 72-76.