Yıl 2017, Cilt 47, Sayı 2, Sayfalar 72 - 76 2017-10-18

Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents

Sibel Döşler [1]

93 143

Recently, because of the rising in multidrug resistance from infectious agents, there is a prompted interest for the development of new antimicrobial agents and new therapeutic strategies to combat the infections caused by the resistant bacteria. Among them, the natural bactericidal compounds, such as antimicrobial cationic peptides (AMPs) seems very promising agents. AMPs are the important component of the innate immune response to the surrounding microorganisms. This substances which can be isolated from most of the living organisms, have various activity like broad spectrum antibacterial, antifungal, antiviral, and antiprotozoal. However there are some resistance mechanisms that affects the AMPs, because of the rapid action and existing more than one mechanism of action, development of resistance to AMPs is quite rare. Due to their many advantages and characteristics, AMPs looks like a good candidate for being a new generation, active antimicrobial agent for antimicrobial chemotherapy against especially multi drug resistant bacteria and biofilms, either alone or in combination. 
Antimicrobial peptides,antibiotic,resistance
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Konular Farmakoloji ve Eczacılık
Dergi Bölümü Review

Yazar: Sibel Döşler
E-posta: sibel.dosler@xn--istanbul-o0e.edu.tr
Kurum: Department of Pharmaceutical Microbiology, Faculty of Pharmacy, İstanbul University, 34116, İstanbul-Turkey
Ülke: Turkey

Bibtex @derleme { iujp345001, journal = {Istanbul Journal of Pharmacy}, issn = {2548-0731}, address = {İstanbul Üniversitesi}, year = {2017}, volume = {47}, pages = {72 - 76}, doi = {}, title = {Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents}, key = {cite}, author = {Döşler, Sibel} }
APA Döşler, S . (2017). Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents. Istanbul Journal of Pharmacy, 47 (2), 72-76. Retrieved from http://www.dergipark.gov.tr/iujp/issue/31503/345001
MLA Döşler, S . "Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents". Istanbul Journal of Pharmacy 47 (2017): 72-76 <http://www.dergipark.gov.tr/iujp/issue/31503/345001>
Chicago Döşler, S . "Antimicrobial peptides: Coming to the end of antibiotic era, the most promising agents". Istanbul Journal of Pharmacy 47 (2017): 72-76
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